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产品名称:
anti-IL-38, mAb (Nhat-1)
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别名:
Interleukin-38; Interleukin-1 Family Member 10; IL-1F10
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产品描述:
IL-38 (IL-1F10) belongs to the IL-1 family of proteins. IL-38 is expressed in heart, placenta, fetal liver, spleen, thymus and tonsil. The expression in a variety of immune tissues and similarity to IL-1Ra suggest a role of IL-38 as a IL-1 family receptor antagonist. Il-38 inhibits IL-36 signaling by binding to IL-1R6. IL-38 (aa 20-152) is released from apoptotic cells to limit inflammatory macrophage and downstream Th17 activation by blocking IL1RAPL1 (Interleukin-1 receptor accessory protein-like 1, TIGIRR-2) signaling. IL-38 is unregulated during some autoimmune diseases such as Systemic Lupus Erythematosus.
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反应种属:
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宿主来源:
Purified from concentrated hybridoma tissue culture supernatant.
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实验应用:
ELISA, WB
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靶标/特异性:
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同种型:
Mouse IgG2bkappa.
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推荐稀释度:
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免疫原:
Recombinant human IL-38.
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免疫原种属:
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克隆性:
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克隆号:
Nhat-1
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纯化方式:
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偶联:
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产品浓度:
1mg/ml
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表达系统:
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阳性对照:
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保存温度:
-20°C
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运输温度:
BLUE ICE
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细胞定位:
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预期分子量:
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产品形式:
liquid
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存储溶液:
Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.
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有效期:
Stable for at least 1 year after receipt when stored at -20°C.
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产地:
瑞士
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外观:
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URL:
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灵敏度:
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检测方法:
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样本类型:
Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.
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产品特点:
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纯度:
>95% (SDS-PAGE)
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生物活性:
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PubChem CID: