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anti-ANGPTL4 (human), mAb (Kairos-1)
品牌： Adipogen
产品货号： AG-20A-0038-C050
规格： 50 ug

报价：
折后价：

数量： - +
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  • 产品名称:
    anti-ANGPTL4 (human), mAb (Kairos-1)
  • 别名:
    Angiopoietin-like Protein 4; FIAF; Fasting-induced Adipose Factor; HFARP; Hepatic Fibrinogen/Angiopoietin-related Protein
  • 产品描述:
    ANGPTL4 mainly expressed in endothelial cells (hypoxia-induced). Regulates angiogenesis and modulates tumorgenesis and directly regulates lipid, glucose, and energy metabolism. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. ANGPTL4 is a protein consisting of an N-terminal coiled-coil domain and a C-terminal fibrinogen-like domain (FLD). Both domains have distinct biological functions. The coiled-coil domain is responsible for the inhibitory effects on lipoprotein lipase (LPL) converting the active form of LPL into an inactive form, and the FLD domain mediates its antiangiogenic functions. The coiled coil and the FLD domains are separated by a short linker that can be cleaved after secretion. ANGPTL4 appears on the cell surface as the full-length form, where it can be released by heparin treatment. ANGPTL4 protein is then proteolytically cleaved by proprotein convertases (PCs), including furin, PC5/6, paired basic amino acid-cleaving enzyme 4, and PC7.
  • 反应种属:
  • 宿主来源:
  • 实验应用:
    ELISA, IHC, WB
  • 靶标/特异性:
  • 同种型:
    Mouse IgG1kappa
  • 推荐稀释度:
  • 免疫原:
    Recombinant human ANGPTL4.
  • 免疫原种属:
  • 克隆性:
  • 克隆号:
    Kairos-1
  • 纯化方式:
  • 偶联:
  • 产品浓度:
    1mg/ml
  • 表达系统:
  • 阳性对照:
  • 保存温度:
    -20°C
  • 运输温度:
    BLUE ICE
  • 细胞定位:
  • 预期分子量:
  • 产品形式:
    liquid
  • 存储溶液:
    Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives.
  • 有效期:
    Stable for at least 1 year after receipt when stored at -20°C.
  • 产地:
    瑞士
  • 外观:
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  • 功能与背景:
  • URL:
  • 灵敏度:
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  • 检测方法:
  • 样本类型:
    Liquid. 0.2µm-filtered solution in PBS, pH 7.4. Contains no preservatives.
  • 产品特点:
  • 纯度:
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  • 分子式:
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  • PubChem CID:
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