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anti-ACE2 (human), mAb (blocking) (AC384) (preservative free)
品牌: Adipogen
产品货号: AG-20A-0037PF-C500
规格: 500 ug

报价:
折后价:

数量: - +
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
  • 产品名称:
    anti-ACE2 (human), mAb (blocking) (AC384) (preservative free)
  • 别名:
    SARS Receptor; Angiotensin-converting Enzyme 2; ACEH; Metalloprotease MPROT15; SARS-CoV-2 Receptor
  • 产品描述:
    Angiotensin-converting enzyme2 (ACE2) is an ectoenzyme (carboxypeptidase) with an extracellular catalytic domain that predominantly localizes at the plasma membrane and is thereby able to hydrolyze circulating peptides. ACE2 has approximately 42% sequence identity with ACE and its cytoplasmic and transmembrane domains show 48% homology to the protein collectrin, that plays a critical role in the amino acid absorption of the kidney. ACE2 converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. ACE2 is involved in the regulation of systemic blood pressure and has direct effects on cardiac functions. It is expressed predominantly in endothelial cells of the lung, gut, heart and kidney. ACE2 together with the protease TMPRSS2 acts as a functional receptor for SARS coronavirus as well as for the new highly pathogenic coronavirus, 2019-nCoV/SARS-CoV-2, which is cause for pneumonia COVID-19.
  • 反应种属:
  • 宿主来源:
  • 实验应用:
    ELISA, FUNC (Blocking), WB
  • 靶标/特异性:
  • 同种型:
    Mouse IgG1kappa
  • 推荐稀释度:
  • 免疫原:
    Recombinant human ACE2.
  • 免疫原种属:
  • 克隆性:
  • 克隆号:
    AC384
  • 纯化方式:
  • 偶联:
    Preservative Free
  • 产品浓度:
    1mg/ml
  • 表达系统:
  • 阳性对照:
  • 保存温度:
    -20°C
  • 运输温度:
    BLUE ICE
  • 细胞定位:
  • 预期分子量:
  • 产品形式:
    liquid
  • 存储溶液:
    Liquid. In PBS.
  • 有效期:
    Stable for at least 1 year after receipt when stored at -20°C.
  • 产地:
    瑞士
  • 外观:
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  • 功能与背景:
  • URL:
  • 灵敏度:
  • 检测范围:
  • 检测方法:
  • 样本类型:
    Liquid. In PBS.
  • 产品特点:
  • 纯度:
  • 生物活性:
  • 内毒素水平:
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  • 分子式:
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