-
产品名称:
TrkB Antibody / NTRK2
-
别名:
-
产品描述:
The Trk proto-oncogene encodes a tyrosine protein kinase, Trk A, also designated Trk gp140, that serves as a receptor for certain neurotrophic factors including nerve growth factor (NGF) and neurotrophin-3 (NT-3). Trk B is a tyrosine kinase gene highly related to Trk A. The brain-derived neurotrophic factor (BDNF) and NT-3, but not NGF, can induce rapid phosphorylation on tyrosine of Trk B gp145, one of the receptors encoded by NTRK2, although BDNF elicits a response at least two orders of magnitude greater than NT-3. Thus it appears that Trk B gp145 may represent a neurotrophic receptor for BDNF and NT-3. The third member of the Trk family of tyrosine kinases, Trk C, encodes a protein designated Trk C gp145 that is preferentially expressed in brain tissue, is equally related to Trk A and Trk B and is a functional receptor for NT-3.
-
反应种属:
Human
-
宿主来源:
Mouse
-
实验应用:
IHC-P
-
靶标/特异性:
-
同种型:
Mouse IgG2, kappa
-
推荐稀释度:
-
免疫原:
A recombinant partial protein sequence (within amino acids 250-450) from the human protein was used as the immunogen for the TrkB antibody.
-
免疫原种属:
-
克隆性:
Monoclonal (mouse origin)
-
克隆号:
-
纯化方式:
Protein A/G affinity
-
偶联:
-
产品浓度:
-
表达系统:
-
阳性对照:
-
保存温度:
Aliquot the TrkB antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
-
运输温度:
-
细胞定位:
-
预期分子量:
-
产品形式:
-
存储溶液:
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
-
有效期:
-
产地:
美国
-
外观:
-
生产商:
-
功能与背景:
-
URL:
-
灵敏度:
-
检测范围:
-
检测方法:
-
样本类型:
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
-
产品特点:
-
纯度:
-
生物活性:
-
内毒素水平:
-
来源:
-
表达方式:
-
Accession #:
-
CAS号:
-
分子式:
-
溶解度:
-
PubChem CID: