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Clusterin Antibody / Apolipoprotein J / APO-J
品牌： NSJ Bio
产品货号： V5240-100UG
规格： 100 ug

报价：
折后价：

数量： - +
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  • 产品名称:
    Clusterin Antibody / Apolipoprotein J / APO-J
  • 别名:
  • 产品描述:
    Clusterin, also designated complement lysis inhibitor (CLI), apolipoprotein J (APOJ), sulfated glycoprotein 2 (SGP2), SP40 and testosterone-repressed prostate message 2 (TRPM2), is a secretory, heterodimeric glycoprotein that influences immune regulation, cell adhesion, transformation, lipid transportation, tissue remodeling, membrane recycling and cell-cell interactions. Clusterin is synthesized as a 449 amino acid polypeptide that is post-translationally cleaved at an internal bond between Arg 227 and Ser 228. Two subunits, Alpha and beta, are associated through disulfide bonds. The beta subunit (also called ApoJAlpha) corresponds to residues 23-227. The Alpha subunit (also called ApoJbeta) corresponds to residues 228-449. Overexpression of Clusterin appears to be more common in late stages of mammary tumor progression. Clusterin markedly influences beta-Amyloid structure and neuritic toxicity in vivo and may influence Alzheimer s pathogenesis.
  • 反应种属:
    Human
  • 宿主来源:
    Rabbit
  • 实验应用:
    IHC-P
  • 靶标/特异性:
  • 同种型:
    Rabbit IgG, kappa
  • 推荐稀释度:
  • 免疫原:
    A recombinant partial protein sequence (within amino acids 249-449) from the human protein was used as the immunogen for the Clusterin antibody.
  • 免疫原种属:
  • 克隆性:
    Recombinant Rabbit Monoclonal
  • 克隆号:
  • 纯化方式:
    Protein A/G affinity
  • 偶联:
  • 产品浓度:
  • 表达系统:
  • 阳性对照:
  • 保存温度:
    Aliquot the Clusterin antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
  • 运输温度:
  • 细胞定位:
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  • 产品形式:
  • 存储溶液:
    0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
  • 有效期:
  • 产地:
    美国
  • 外观:
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  • 灵敏度:
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  • 检测方法:
  • 样本类型:
    0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
  • 产品特点:
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  • 分子式:
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