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产品名称:
Bcl6 Antibody
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别名:
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产品描述:
Recognizes a protein of 95kDa, which is identified as Bcl-6. Antibody to bcl-6 is helpful in a number of diagnostic settings: (1) In the differential diagnosis of small B-cell lymphoma. Follicular lymphoma will show bcl-6 (and CD10) positivity whereas other small B-cell lymphomas are usually negative. (2) Bcl-6 is an important prognostic marker in diffuse large B-cell lymphomas (DLBCL), where CD10, bcl-6 and MUM1/IRF4 are used to identify germinal center and activated B-cell phenotypes. (3) Bcl-6 can be valuable in distinguishing classical Hodgkin lymphoma from nodular lymphocyte predominant Hodgkin lymphoma (NLPHL). The Reed-Sternberg cells of classical Hodgkin lymphoma are bcl-6 negative whereas the large ( L&H ) cells of NLPHL are bcl-6 positive. In contrast, anti-Bcl-6 rarely stains mantle-cell lymphoma and MALT lymphoma.
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反应种属:
Human
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宿主来源:
Rabbit
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实验应用:
IHC-P
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靶标/特异性:
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同种型:
Rabbit IgG, kappa
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推荐稀释度:
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免疫原:
A recombinant partial protein sequence (within amino acids 1-400) from the human protein was used as the immunogen for the B-Cell Lymphoma 6 antibody.
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免疫原种属:
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克隆性:
Recombinant Rabbit Monoclonal
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纯化方式:
Protein A/G affinity
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保存温度:
Aliquot the B-Cell Lymphoma 6 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
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存储溶液:
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
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产地:
美国
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样本类型:
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
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