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产品名称:
Mucin 4 antibody [ZR201]
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别名:
mucin 4, cell surface associated , ASGP , HSA276359 , MUC-4
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产品描述:
Mucin 4, a membrane-bound mucin, is the human homolog of the rat sialomucin complex (SMC). The Mucin 4 gene is the predominant mucin gene expressed in the normal urothelium and is also expressed in several normal tissues such as trachea, lung and testis. Dysregulation of mucin 4results in high levels of expression in pancreatic tumors and tumor cell lines. Induction of mucin 4 in pancreatic carcinoma by alltrans-retinoic acid is mediated through the retinoic acid receptor-å signaling pathway. MUC-4 is a very specific (100%) andsensitive (90%) marker of lung adenocarcinomas and is negative for mesotheliomas. MUC4 is expressed in many human adenocarcinomas. It is specifically expressed in lowgrade fibromyxoid sarcoma. Reportedly, MUC-4 expression in invasive ductal carcinoma of the pancreas is an independent factor for poor prognosis.
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反应种属:
Human
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宿主来源:
Rabbit
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实验应用:
IHC-P
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靶标/特异性:
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同种型:
IgG
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推荐稀释度:
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免疫原:
Recombinant fragment (around aa 1730-1864) of human MUC4 prote
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免疫原种属:
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克隆性:
Monoclonal
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克隆号:
ZR201
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纯化方式:
Purified IgG
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偶联:
Unconjugated
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产品浓度:
batch dependent (Please refer to the vial label for the specific concentration.)
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表达系统:
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阳性对照:
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保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. Store at 4ºC.
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运输温度:
4°C
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细胞定位:
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预期分子量:
232
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产品形式:
Liquid
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存储溶液:
Tris‐HCl buffer, 0.2% BSA, 0.09% sodium azide.
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有效期:
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产地:
美国
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样本类型:
Tris‐HCl buffer, 0.2% BSA, 0.09% sodium azide.
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