-
产品名称:
GluR2 antibody [GT1283]
-
别名:
glutamate ionotropic receptor AMPA type subunit 2 , GLUR2 , GLURB , GluA2 , GluR-K2 , HBGR2
-
产品描述:
-
反应种属:
Human, Mouse, Rat
-
宿主来源:
Rabbit
-
实验应用:
ICC/IF, IHC-P, WB
-
靶标/特异性:
-
同种型:
IgG
-
推荐稀释度:
-
免疫原:
A synthesized peptide derived from human GluR2.
-
免疫原种属:
-
克隆性:
Monoclonal
-
克隆号:
GT1283
-
纯化方式:
Purified by affinity chromatography
-
偶联:
Unconjugated
-
产品浓度:
1.3 mg/ml (Please refer to the vial label for the specific concentration.)
-
表达系统:
-
阳性对照:
-
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
-
运输温度:
4°C
-
细胞定位:
-
预期分子量:
99
-
产品形式:
Liquid
-
存储溶液:
PBS pH7.3, 0.05% BSA, 50% Glycerol, 0.02% Sodium azide.
-
有效期:
-
产地:
美国
-
外观:
-
生产商:
-
功能与背景:
Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, GRIA1-4. The subunit encoded by this gene (GRIA2) is subject to RNA editing (CAG->CGG; Q->R) within the second transmembrane domain, which is thought to render the channel impermeable to Ca(2+). Human and animal studies suggest that pre-mRNA editing is essential for brain function, and defective GRIA2 RNA editing at the Q/R site may be relevant to amyotrophic lateral sclerosis (ALS) etiology. Alternative splicing, resulting in transcript variants encoding different isoforms, (including the flip and flop isoforms that vary in their signal transduction properties), has been noted for this gene. [provided by RefSeq, Jul 2008]
-
URL:
-
灵敏度:
-
检测范围:
-
检测方法:
-
样本类型:
PBS pH7.3, 0.05% BSA, 50% Glycerol, 0.02% Sodium azide.
-
产品特点:
-
纯度:
-
生物活性:
-
内毒素水平:
-
来源:
-
表达方式:
-
Accession #:
-
CAS号:
-
分子式:
-
溶解度:
-
PubChem CID: