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alpha A Crystallin antibody [GT1276]
品牌: GeneTex
产品货号: GTX03188
规格: 100μl

报价:
折后价:

数量: - +
产品详情
* 以下信息仅供参考,详情请以原厂网站为准
  • 产品名称:
    alpha A Crystallin antibody [GT1276]
  • 别名:
    crystallin alpha A , CRYA1 , CTRCT9 , HSPB4
  • 产品描述:
  • 反应种属:
    Mouse, Rat
  • 宿主来源:
    Rabbit
  • 实验应用:
    IHC-P, WB
  • 靶标/特异性:
  • 同种型:
    IgG
  • 推荐稀释度:
  • 免疫原:
    A synthesized peptide derived from human CRYAA.
  • 免疫原种属:
    Human
  • 克隆性:
    Monoclonal
  • 克隆号:
    GT1276
  • 纯化方式:
    Purified by affinity chromatography
  • 偶联:
    Unconjugated
  • 产品浓度:
    3 mg/ml (Please refer to the vial label for the specific concentration.)
  • 表达系统:
  • 阳性对照:
  • 保存温度:
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
  • 运输温度:
    4°C
  • 细胞定位:
  • 预期分子量:
  • 产品形式:
    Liquid
  • 存储溶液:
    PBS pH7.3, 0.05% BSA, 50% Glycerol, 0.02% Sodium azide.
  • 有效期:
  • 产地:
    美国
  • 外观:
  • 生产商:
  • 功能与背景:
    Mammalian lens crystallins are divided into alpha, beta, and gamma families. Alpha crystallins are composed of two gene products: alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (HSP20) family. They act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone; instead they hold them in large soluble aggregates. Post-translational modifications decrease the ability to chaperone. These heterogeneous aggregates consist of 30-40 subunits; the alpha-A and alpha-B subunits have a 3:1 ratio, respectively. Two additional functions of alpha crystallins are an autokinase activity and participation in the intracellular architecture. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Alpha-A and alpha-B gene products are differentially expressed; alpha-A is preferentially restricted to the lens and alpha-B is expressed widely in many tissues and organs. Defects in this gene cause autosomal dominant congenital cataract (ADCC). [provided by RefSeq, Jan 2014]
  • URL:
  • 灵敏度:
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  • 检测方法:
  • 样本类型:
    PBS pH7.3, 0.05% BSA, 50% Glycerol, 0.02% Sodium azide.
  • 产品特点:
  • 纯度:
  • 生物活性:
  • 内毒素水平:
  • 来源:
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  • CAS号:
  • 分子式:
  • 溶解度:
  • PubChem CID:
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