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AKT1 (phospho Ser124) antibody [GT1268]
品牌： GeneTex
产品货号： GTX03180
规格： 100μl

报价：
折后价：

数量： - +
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  • 产品名称:
    AKT1 (phospho Ser124) antibody [GT1268]
  • 别名:
    AKT serine/threonine kinase 1 , AKT , CWS6 , PKB , PKB-ALPHA , PRKBA , RAC , RAC-ALPHA
  • 产品描述:
  • 反应种属:
    Human
  • 宿主来源:
    Rabbit
  • 实验应用:
    WB
  • 靶标/特异性:
  • 同种型:
    IgG
  • 推荐稀释度:
  • 免疫原:
    A phospho specific peptide corresponding to residues surrounding S124 of human AKT1.
  • 免疫原种属:
  • 克隆性:
    Monoclonal
  • 克隆号:
    GT1268
  • 纯化方式:
    Purified by affinity chromatography
  • 偶联:
    Unconjugated
  • 产品浓度:
    1.43 mg/ml (Please refer to the vial label for the specific concentration.)
  • 表达系统:
  • 阳性对照:
  • 保存温度:
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
  • 运输温度:
    4°C
  • 细胞定位:
  • 预期分子量:
    56
  • 产品形式:
    Liquid
  • 存储溶液:
    PBS pH7.3, 0.05% BSA, 50% Glycerol, 0.02% Sodium azide.
  • 有效期:
  • 产地:
    美国
  • 外观:
  • 生产商:
  • 功能与背景:
    The serine-threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum-starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet-derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3-kinase. In the developing nervous system AKT is a critical mediator of growth factor-induced neuronal survival. Survival factors can suppress apoptosis in a transcription-independent manner by activating the serine/threonine kinase AKT1, which then phosphorylates and inactivates components of the apoptotic machinery. Mutations in this gene have been associated with the Proteus syndrome. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2011]
  • URL:
  • 灵敏度:
  • 检测范围:
  • 检测方法:
  • 样本类型:
    PBS pH7.3, 0.05% BSA, 50% Glycerol, 0.02% Sodium azide.
  • 产品特点:
  • 纯度:
  • 生物活性:
  • 内毒素水平:
  • 来源:
  • 表达方式:
  • Accession #:
  • CAS号:
  • 分子式:
  • 溶解度:
  • PubChem CID:
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