产品描述:
Malathion-d10 is intended for use as an internal standard for the quantification of malathion (Item No. 22998) by GC- or LC-MS. Malathion is an organophosphate insecticide that inhibits acetylcholinesterase (AChE; IC50s = 370 and 160 µM for free and immobilized AChE, respectively, from bovine erythrocytes).{37737} It is ovicidal and adulticidal to laboratory colonies of body lice when used at concentrations of 0.001 and 0.05%, respectively.{37738} It is toxic to rats (LD50 = 750 mg/kg) and teratogenic to zebrafish when used at concentrations ranging from 2 to 3 mg/L.{37739,37740} Formulations containing malathion have been used in the treatment of lice.